Karl Y Hostetler Selected Research

octadecyloxyethyl-cyclic-cidofovir

4/2011

Intraocular pharmacokinetics of a crystalline lipid prodrug, octadecyloxyethyl-cyclic-cidofovir, for cytomegalovirus retinitis.

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Karl Y Hostetler Research Topics

Disease

25	Infections 01/2023 - 02/2002
12	Vaccinia 05/2011 - 01/2004
11	Cowpox 05/2011 - 03/2003
6	Retinitis 01/2015 - 02/2002
5	COVID-19 01/2023 - 01/2021
5	Smallpox (Variola) 05/2011 - 01/2004
4	Ectromelia (Phocomelia) 05/2011 - 10/2006
4	Body Weight (Weight, Body) 01/2011 - 09/2004
4	Poxviridae Infections 10/2010 - 03/2003
3	HIV Infections (HIV Infection) 05/2009 - 08/2006
2	Cytomegalovirus Retinitis 04/2011 - 08/2005
2	Cytomegalovirus Infections (Inclusion Disease) 01/2011 - 08/2004
2	Neoplasms (Cancer) 01/2010 - 01/2006
2	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2010 - 01/2006
2	Virus Diseases (Viral Diseases) 07/2009 - 01/2005
2	Infectious Ectromelia 03/2007 - 01/2004
2	Acquired Immunodeficiency Syndrome (AIDS) 08/2004 - 08/2003
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2018
1	Papillomavirus Infections 01/2018
1	Leukemia 01/2018
1	Retinal Diseases 01/2015
1	VLCAD deficiency 02/2013
1	Proliferative Vitreoretinopathy 01/2012
1	Toxic Optic Neuropathy 01/2012
1	Papilloma (Papillomatosis) 10/2010
1	Uterine Cervical Dysplasia 01/2010
1	Hepatitis B 05/2009
1	Inflammation (Inflammations) 10/2007
1	Edema (Dropsy) 10/2007
1	Contagious Ecthyma 07/2007
1	Retinoblastoma (Glioblastoma, Retinal) 01/2006
1	Heart Diseases (Heart Disease) 08/2004
1	Skin Diseases (Skin Disease) 08/2004
1	Respiratory Tract Infections (Respiratory Tract Infection) 05/2004
1	Cataract (Cataracts) 02/2002

Drug/Important Bio-Agent (IBA)

22	Cidofovir (Vistide)FDA Link 01/2015 - 03/2003
19	EstersIBA 01/2023 - 01/2004
18	Antiviral Agents (Antivirals)IBA 01/2023 - 02/2002
13	brincidofovirIBA 01/2015 - 03/2003
11	NucleosidesIBA 10/2018 - 03/2003
10	LipidsIBA 01/2015 - 01/2004
9	ProdrugsIBA 01/2023 - 05/2004
8	Organophosphonates (Phosphonates)IBA 01/2018 - 10/2006
6	9- (S)- (3- hydroxy- 2- (phosphonomethoxy)propyl)adenineIBA 08/2008 - 03/2006
5	remdesivirIBA 01/2023 - 01/2021
5	Ether (Diethyl Ether)IBA 09/2004 - 01/2004
3	DNA (Deoxyribonucleic Acid)IBA 05/2011 - 01/2006
3	Tenofovir (Viread)FDA Link 05/2009 - 02/2007
3	Adenine FDA LinkGeneric 11/2007 - 07/2007
3	Retinaldehyde (Retinal)IBA 10/2007 - 02/2002
2	molnupiravirIBA 06/2021 - 01/2021
2	nirmatrelvirIBA 06/2021 - 01/2021
2	Cytarabine (Cytosar-U)FDA LinkGeneric 01/2018 - 01/2012
2	9-((2-phosphonylmethoxy)ethyl)guanineIBA 01/2018 - 01/2010
2	adefovirIBA 01/2018 - 05/2009
2	GuanineIBA 01/2010 - 12/2009
2	purineIBA 12/2006 - 05/2004
2	SaltsIBA 01/2006 - 02/2002
2	VaccinesIBA 08/2004 - 08/2003
2	Smallpox Vaccine (Vaccine, Smallpox)FDA Link 08/2004 - 01/2004
1	Phospholipids (Phosphatides)FDA LinkGeneric 01/2023
1	EthersIBA 01/2023
1	Glycerol (Glycerine)FDA LinkGeneric 01/2023
1	Anti-Retroviral Agents (Antiretroviral Agents)IBA 11/2019
1	MicellesIBA 01/2015
1	Long-Chain Acyl-CoA Dehydrogenase (Long-Chain-Acyl-Coenzyme A Dehydrogenase)IBA 02/2013
1	hexadecyloxypropyl cytarabine 3',5'-cyclic monophosphateIBA 01/2012
1	hexadecyloxypropyl cytarabine 5'-monophosphateIBA 01/2012
1	octadecyloxyethyl-cyclic-cidofovirIBA 04/2011
1	octadecyloxyethyl 9-(2-(phosphonomethoxy)ethyl)guanineIBA 01/2010
1	9- (3- hydroxy- 2- phosphonomethoxypropyl)guanineIBA 12/2009
1	ThymineIBA 12/2009
1	9- (3- hydroxy- 2- phosphonomethoxypropyl)- 2,6- diaminopurineIBA 12/2009
1	cyclic- 9- (3- hydroxy- 2- phosphonylmethoxypropyl)adenineIBA 10/2007
1	hexadecyloxypropyl 9-(2-(phosphonomethoxy)propyl)adenineIBA 10/2007
1	CytosineIBA 07/2007
1	adefovir dipivoxil (Hepsera)FDA Link 02/2007
1	S 2242IBA 12/2006
1	Oncogene Proteins (Oncogene Protein)IBA 01/2006
1	hexadecyloxypropyl-cyclic cidofovirIBA 06/2005
1	Ribavirin (Virazole)FDA LinkGeneric 05/2004
1	Investigational DrugsIBA 01/2004
1	Ammonium CompoundsIBA 02/2002
1	1- O- hexadecyl- propanediol- 3- phospho- ganciclovirIBA 02/2002

Therapy/Procedure

8	Therapeutics 01/2011 - 02/2002
2	Intravenous Administration 12/2021 - 08/2021
2	Intravitreal Injections 01/2015 - 02/2002
2	Injections 10/2007 - 02/2002
1	Oral Administration 08/2008
1	Drug Therapy (Chemotherapy) 12/2006
1	Organ Transplantation 08/2004